Patient Information, Including Boxed Warning • Important Safety Information • Full Prescribing Information   

We're Sorry. The page you are looking for wasn't found (Error 404)
Here are some ways to help you find the page you are looking for:
Go to home page for www.premarin.com

• If you entered the URL manually, please check your spelling and try again.
• If you think this was a service error, please Contact us

What is the most important information you should know about PREMARIN (an estrogen mixture)?

• Estrogens increase the chance of getting cancer of the uterus.

Report any unusual vaginal bleeding right away while you are using these products. Vaginal bleeding after menopause may be a warning sign of cancer of the uterus (womb). Your healthcare provider should check any unusual vaginal bleeding to find out the cause.

• Do not use estrogens with or without progestins to prevent heart disease, heart attacks, strokes, or dementia.

Using estrogens, with or without progestins, may increase your chance of getting heart attacks, strokes, breast cancer, and blood clots. Using estrogens, with or without progestins, may increase your chance of getting dementia, based on a study of women age 65 years or older. You and your health care provider should talk regularly about whether you still need treatment with estrogens.

PREMARIN should be used at the lowest effective dose and for the shortest duration consistent with your treatment goals and risks. If you are using or are considering using PREMARIN only to treat your symptoms of vaginal dryness, consider topical therapies first. If you are using or are considering using PREMARIN only to prevent osteoporosis due to menopause, talk with your healthcare professional about whether a different treatment or medicine without estrogens might be better for you.

PREMARIN should not be used if you have unusual vaginal bleeding, have or had cancer of the breast or uterus, had a stroke or heart attack, have or had blood clots or liver problems, have had a bleeding disorder, are allergic to any of the ingredients in PREMARIN, or think you may be pregnant. In general, the addition of a progestin is recommended for women with a uterus to reduce the chance of getting cancer of the uterus.

In a clinical trial, the most commonly reported (≥5%) side effects that occurred more frequently with PREMARIN than with placebo were vaginitis due to yeast or other causes, vaginal bleeding, painful menstruation, and leg cramps.

PREMARIN (conjugated estrogens tablets, USP) is a prescription treatment used after menopause. PREMARIN is used after menopause to reduce moderate to severe hot flashes; to treat moderate to severe dryness, itching, and burning, in and around the vagina; and to help reduce your chances of getting osteoporosis (thin weak bones).

Home  |  About Menopause  |  About PREMARIN  |  Talking With Your Doctor  |  Menopause Resources  |  Site Map

Contact Us  |  About Pfizer  |  Privacy Policy  |  Terms of use

The health information contained herein is provided for educational purposes only and is not intended to replace discussions with a healthcare provider. All decisions regarding patient care must be made with a healthcare provider, considering the unique characteristics of the patient.

The product information provided in this site is intended for residents of the United States.
The products discussed herein may have different product labeling in different countries.

PRM00326