PREMARIN (conjugated estrogens) is used after menopause to reduce moderate to severe hot flashes.

Woman in field Woman in field
Flame Icon
Menopause, Hot Flashes, and you

Keep track of your hot flashes and learn more about how they relate to menopause

 Savings Card Icon
IF ELIGIBLE, YOU CAN SAVE ON PREMARIN

Pay as little as $15 per month* for your PREMARIN prescription

*Terms and Conditions apply.

*Terms and Conditions apply. This Card is not health insurance. This Card is only accepted at participating pharmacies. No membership fees are associated with this Card. Eligible patients will pay as little as $15 with a savings of up to $55 per prescription filled. Limit 12 offers per calendar year. Maximum savings of $660 per calendar year. If you are enrolled in a state or federally funded prescription insurance program, you may not use the savings card even if you elect to be processed as an uninsured (cash-paying) patient. Exp. 12/31/20. See below for full Terms and Conditions. For help processing, please call 1-855-477-7309. Pfizer: Attn: PREMARIN, 235 East 42nd Street, NY, NY 10017, www.pfizer.com. 

IMPORTANT SAFETY INFORMATION AND INDICATION

Using estrogen-alone may increase your chance of getting cancer of the uterus (womb). Report any unusual vaginal bleeding right away while you are using PREMARIN. Vaginal bleeding after menopause may be a warning sign of cancer of the uterus (womb). Your healthcare provider should check any unusual vaginal bleeding to find out the cause.

Do not use estrogens with or without progestins to prevent heart disease, heart attacks, strokes or dementia (decline in brain function).

Using estrogen-alone may increase your chances of getting strokes or blood clots. Using estrogens with progestins may increase your chances of getting heart attacks, strokes, breast cancer, or blood clots.

Using estrogens, with or without progestins, may increase your chance of getting dementia, based on a study of women 65 years of age or older.

Estrogens should be used at the lowest dose possible, only for as long as needed. You and your healthcare provider should talk regularly about whether you still need treatment.

PREMARIN should not be used if you have unusual vaginal bleeding, have or had cancer, had a stroke or heart attack, have or had blood clots or liver problems, have a bleeding disorder, are allergic to any of its ingredients, or think you may be pregnant. In general, the addition of a progestin is recommended for women with a uterus to reduce the chance of getting cancer of the uterus.

Estrogens increase the risk of gallbladder disease. Discontinue estrogen if loss of vision, pancreatitis, or liver problems occur. If you take thyroid medication, consult your healthcare provider, as use of estrogens may change the amount needed.

The most common (≥5%) side effects are abdominal pain, asthenia, pain, back pain, headache, flatulence, nausea, depression, insomnia, breast pain, endometrial hyperplasia, leucorrhea, vaginal hemorrhage, and vaginitis.

INDICATION

PREMARIN is used after menopause to reduce moderate to severe hot flashes.

Please see Full Prescribing Information, including BOXED WARNING and Patient Information.

Patients should always ask their doctors for medical advice about adverse events.